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Symbol
Name
ID
Sash3
SAM and SH3 domain containing 3
MGI:1921381
Phenotype annotations related to immune system
Darker colors indicate more annotations

Mouse Phenotypes
decreased T cell proliferation
abnormal CD4-positive T cell differentiation
abnormal CD8-positive, alpha-beta T cell differentiation
decreased double-positive T cell number
decreased marginal zone B cell number
abnormal B cell morphology
abnormal T cell morphology
abnormal B cell physiology
decreased IgG1 level
decreased IgG2a level
decreased IgG level
decreased IgM level
abnormal marginal zone B cell physiology
abnormal immune system organ morphology
decreased Peyer's patch number
lymphoid hypoplasia
abnormal humoral immune response
decreased interferon-gamma secretion
decreased interleukin-10 secretion
decreased interleukin-2 secretion
decreased interleukin-4 secretion
decreased tumor necrosis factor secretion
abnormal inflammatory response
increased length of allograft survival
Availability Mouse Genotype
Sash3tm1Hlz/Sash3tm1Hlz

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory