Symbol Name ID |
Sash3
SAM and SH3 domain containing 3 MGI:1921381 |
Darker colors indicate more annotations |
Mouse Phenotypes | decreased T cell proliferation |
abnormal CD4-positive T cell differentiation |
abnormal CD8-positive, alpha-beta T cell differentiation |
decreased double-positive T cell number |
decreased marginal zone B cell number |
abnormal B cell morphology |
abnormal T cell morphology |
abnormal B cell physiology |
decreased IgG1 level |
decreased IgG2a level |
decreased IgG level |
decreased IgM level |
abnormal marginal zone B cell physiology |
abnormal immune system organ morphology |
decreased Peyer's patch number |
lymphoid hypoplasia |
abnormal humoral immune response |
decreased interferon-gamma secretion |
decreased interleukin-10 secretion |
decreased interleukin-2 secretion |
decreased interleukin-4 secretion |
decreased tumor necrosis factor secretion |
abnormal inflammatory response |
increased length of allograft survival |
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Availability | Mouse Genotype | ||||||||||||||||||||||||
Sash3tm1Hlz/Sash3tm1Hlz |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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